The monograph continues to study the important problems of international relations between the United States and Russia as the main players in the formation of the modern world order. It examined a number of common problems (international institutions), issues of international security (evolution of approaches to arms control), the role of the United States and the Russian Federation in the Syrian conflict, the situation with the development of Eurasian integration, the internal political situation in the United States and the prospects for the development of Russian-American relations, etc. The book can be used in the faculties of international relations and political science. It is of interest to everyone who follows the development of modern international relations and the policy of the two powers.