Alfred Doblin is one of the most important twentieth-century German writers. This volume reassesses the uniquely interdisciplinary quality of his texts, which are paradigms of the encounter between literary and scientific modernity. It analyses Doblin's best-known literary works as well as his medical essays, political journalism and autobiographical texts, and it situates him in relation to other writers such as Heine, Benn, Brecht and Sebald. Wide-ranging and with contributions in English and German, this is a valuable study for students and advanced researchers alike.