In the theoretical part of the manual, sections on the first and second laws of thermodynamics are covered, the basic concepts of physical chemistry are given. The practical part of the book contains methods for performing a laboratory workshop, options for a calculation task with a solution algorithm, and knowledge control tests. The manual is intended for organizing independent work of students in preparation for lecture, practical and laboratory classes, as well as for intermediate control of knowledge in the course "Physical Chemistry." The manual is intended for students of chemical-technological directions and specialties of universities.