The guide provides answers to the most frequently asked questions about vaccines and vaccination, as well as counterarguments to anti-vaccine arguments. To facilitate dialogue with people not related to medicine, the authors of the guide outlined some difficult to understand issues (in particular, immunological ones) in a simple and understandable language, without abuse of special terminology. The main task of this book is to help practical doctors, competently and reasonably defending their position, to answer questions from the population regarding vaccine prevention.