Spider-Woman is back, and she's pulling no punches! Jessica Drew hasn't been feeling like herself lately. When the angry, irritable and unwell Spider-Woman takes a simple security gig to help her get back on her feet, she finds herself besieged by unknown forces out to destroy everything around her. But what does Jessica's illness have to do with the daughter of her old nemesis, Otto Vermis? And how does a shipment of black-market spiders fit in? Jessica Drew is fighting for her life while someone is pulling the strings of her web. She soon finds herself forced back to where it all began - Wundagore Mountain, the nightmarish place that gave her powers - but who is making her relive her traumas? The answers are about to get personal! This is the Spider-Woman book you've been waiting for!Road trip - to space! After learning some startling secrets about her family, Jessica Drew goes on a mission to find the one person who might know more: the High Evolutionary! But she s going to need her BFF by her side - and that means it s Captain Marvel team-up time! Before long though, those closest to Spider-Woman will abandon her. Only one person will come to her aid: Octavia Vermis! Octavia has a cure for Jessica, and the prescription is crime! Is Jess willing to resort to theft to gather all the tools needed to fix what s wrong? In the shadow of Knull s invasion, Spider-Woman must put everything on the line - and then cross it! Even if Jess can find the cure for what ails her, will she still have a life worth saving?Jessica Drew is going back to basics! She's been pushed to places she never wants to go again - but she survived. Now, with a new lease on life, it's time to show the world who Spider-Woman truly is! She'll begin with the Brothers of the Sword - but who exactly are these blade-wielding bros? The answer to that is just the beginning. A who's who of Marvel mercenaries want something that Jess has - and needs! Spider-Woman soon finds herself in the sights of Lady Bullseye and more deadly killers in a battle royal across New York City! But when the fight becomes a family affair, someone in the Drew clan will suit up for the first time! Who could it be?! It's the fight of Spider-Woman's life, and you do not want to miss it! Lights! Cameras! Action! Jess is still recovering from her epic showdown with her brother, Aeternum, when she decides to visit her old friend, stuntwoman Lindsay McCabe, on the set of her newest film project. But wait - those assassins aren t in the movie! And they re after Lindsay?! Get ready for your close-up, Jess! Then, when New York Mayor Wilson Fisk starts purging costumed vigilantes from his city, you can bet Spider-Woman is on his list! The Kingpin will do anything to bring her down - including going after her loved ones. It s all on the line for Jessica Drew when Fisk unleashes his insidious endgame! But why is Spider-Woman fighting...Spider-Woman?! And what s worse than Spider-Man s Sinister Six? How about Jess awful assemblage of adversaries: the Anti-Arachnine!