This book "Heart Disease in Women" summarizes the cardiovascular diseases in women. This book consists of a total of 34 chapters organized into 8 sections. These sections describes facts about cardiovascular disease in women and the important topic of cardiovascular disease prevention, sex differences in the effects of leading and most prevalent risk factors in women, topics of resistant and refractory hypertension, cardiac and non-cardiac causes of stoke, relationship of oral contraceptive pills and hormone replacement therapy, deleterious effects of smoking in women, Job stress, strain, burnout, and unemployment. Also the role of autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and antiphospholipid antibody syndrome in atherosclerotic plaque formation, effect of pregnancy and menopause on cardiovascular function, and sex-based differences in the epidemiology, prevalence, clinical manifestation, and management of various types of arrhythmias including atrial fibrillation and ventricular tachycardia, are discussed. Diagnostic testing including the use of ankle-brachial index, gender differences in its values and guidelines used in the management are highlighted.