The scope of the research presented in this publication includes semantic-based integration of data services in smart grids achieved through following the proposed (S2)In-approach developed corresponding to design science guidelines. This approach identifies standards and specifications, which are integrated in order to build the basis for the (S2)In-architecture. A process model is introduced in the beginning, which serves as framework for developing the target architecture. The first step of the process stipulates to define requirements for smart grid ICT-architectures being derived from established studies and divided into two architecture and non-functional requirements (NFR). Based on the architecture requirements, the following specifications have been basically The IEC CIM representing a domain-specific data model, the OPC UA being a communication standard with special respects to information modeling, and WSMO as an approach to realize the concept of Semantic Web Services. The next step specifies to develop both, a semantic information model (integration of CIM and OPC UA) and semantic services (integration of CIM and WSMO). These two components are then combined to obtain the target architecture, which allows precise descriptions of services as well as their combination and semi-automatic execution. Finally, the NFR are considered in order to evaluate the architecture based on simulated, representative use cases. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish -Biomedicine-Oncology-Artificial intelligence-Databases and information systems-Maritime engineering-Nanotechnology-Geoengineering-All aspects of physics-E-governance-E-commerce-The knowledge economy-Urban studies-Arms control-Understanding and responding to terrorism-Medical informatics-Computer Sciences