The textbook includes a block of theoretical information on the methodology of physicochemical methods for the analysis of medicinal substances and pharmaceutical raw materials: devices, execution technique, interpretation of analysis results, as well as examples of solving the most common situational problems in the field of pharmaceutical and pharmacopoeial analyzes within the framework of qualitative and quantitative definitions of active and related substances, covering almost all aspects of the activities of the future pharmacist and pharmacist-analyst in the field of qualitative and quantitative assessment of pharmaceutical substances, extemporal, finished dosage forms and medicinal plant raw materials.