The radio goes quiet while on convoy in Afghanistan, a lost patrol alone in the desert. With his unit and his home base destroyed, Staff Sergeant Brad Thompson suddenly finds himself isolated and in command of a small group of men trying to survive in the Afghan wasteland. The local population has been afflicted with an illness that turns them into rabid animals. They pursue him and his men at every corner and stop. Struggling to hold his team together and unite survivors, he must fight and evade his way to safety.