If global challenges in food production and the impact of ever-declining biodiversity are to be tackled, every country will need plant biologists who have a deep understanding of plant morphology, physiology and genetics, and how these interact to affect plant function in changing environments. These scientists will also need the capacity to use an effective and powerful set of technologies and research strategies. To prepare and inspire our students to become that next generation of researchers and to instill a meaningful involvement in research we created an integrated set of laboratory investigations that we felt truly reflected the mysteries of plant biology and puzzle-solving processes that we had encountered in our research experience.