This book is a compilation of some of the best papers presented at the 15th International Conference on Industrial Engineering and Industrial Management in 2021. The Conference was promoted by ADINGOR (Asociacion para el Desarrollo de la Ingenieria de Organizacion), organized by the University of Burgos, and it took place online on July 8 and 9, 2021.The book highlights some of the latest research advances and cutting-edge analyses of real-world case studies on industrial engineering and industrial management from a wide range of international contexts. It also identifies business applications and the latest findings and innovations in operations management and decision sciences.Industry 4.0: The Power of Data will help academic researchers and practitioners in industrial engineering and industrial management to keep abreast of state-of-the-art developments in these subjects.