The Python 3 language is described: data types, operators, conditions, loops, regular expressions, functions, object-oriented programming tools, working with files and directories, frequently used modules of the standard library. Provides the basics of the SQLite database, the interface to access the database, and how to get data from the Internet. Particular attention is paid to the PyQt 5 library, which allows you to create applications with a graphical interface in Python. Tools for processing signals and events, managing window properties, developing multithreaded applications are considered, the main components (buttons, text fields, lists, tables, menus, toolbars, etc.), options for their placement inside the window, tools for working with databases, multimedia, printing documents and exporting them in Adobe PDF format are described.