Spence Tailor, a lawyer with an actual set of principles, loves his mama, Rose. Rose - with advanced cardiomyopathy and a rare blood type - is scheduled for a heart transplant. But when the president's heart craps out during a photo op three months before the national election, the White House chief of staff orders the FBI to seize the heart that was going to Rose - all in the name of democracy. But Spence isn't about to let anybody steal what rightfully belongs to his mom. So with the help of his reluctant older brother, they hijack the heart, inadvertently kidnap a beautiful cardiac surgery resident, and take to the road in a '65 Mustang - with all the president's men in potentially murderous pursuit.