This book presents new methods of circuit design for guitar electronics, based directly upon U.S. Non-Provisional Patent Applications. By systematic construction of unique series-parallel circuit topologies, the author shows how many series-parallel circuits are possible, including non-matched single-coil pickups, humbucking pickups, and humbucking combinations of matched single-coil pickups. This allows designers to avoid unnecessary and confusing duplicate circuits in pickup switching systems. It shows how electromechanical switches cannot produce the maximum number of tones for more than 2 or 3 pickups. Thus the author discloses an efficient micro-controller and cross-point switch architecture to replace mechanical switches, and allow access to the maximum number of tones. The discussion continues, developing humbucking circuits for odd numbers of matched single-coil pickups, extendable to any odd or even number, greater than 1, using a simplified switching system with very simple rules. It abandons some tones in favor of producing all-humbucking and unique tones, no matter what the switching choice. The author discloses both mechanical and digital switching versions. Then, based on using humbucking basis vectors, the author discloses variable-gain circuits that duplicate all possible switched humbucking tone circuits, and produces all the continuous tone gradations in between. The presentation includes analog and digitally controlled systems. The object of all the give the guitarist or pianist a system which allows going from bright to warm tones and back, without ever needing to know which pickups are used in what combination.