'Techniques in treating infertility have moved on a long way, even in the last four years,' he explains...'I can arrange a meeting for you with our most senior consultant. He can talk you through the new treatment protocols that significantly reduce the need for drugs and the risks of OHSS...' Without even looking in Lesley's direction this time, I can tell her whole body is beginning to shake. I turn to her and my wife's face is a pale mask of horror. Then there are tears. Floods of treats. Tears born of anger, frustration, but most of all, fear. What happens when IVF goes wrong In Frozen, Mike Butcher recounts their experience of undergoing IVF treatment. But when his wife Lesley suffers a near-fatal reaction to the treatment, the couple's lives are thrown into turmoil and their plans to build their family put on ice. After an escalating series of setbacks and heartache, Mike and Lesley are almost resigned to giving up their dreams of parenthood - until they pick up a flyer from a local adoption agency.