As data continues to grow exponentially, knowledge of Data Science and Machine Learning has become more crucial than ever. Machine Learning has grown exponentially; however, the abundance of resources can be overwhelming, making it challenging for new learners. This book aims to address this disparity and cater to learners from various non-technical fields, enabling them to utilize Machine Learning effectively. Adopting a hands-on approach, readers are guided through practical implementations using real datasets and SAS Enterprise Miner, a user-friendly data mining software that requires no programming. Throughout the chapters, two large datasets are used consistently, allowing readers to practice all stages of the data mining process within a cohesive project framework. This book also provides specific guidelines and examples on presenting data mining results and reports, enhancing effective communication with stakeholders. The book begins with Part I, introducing the core concepts of data science, data mining, and Machine Learning. My aim is to present these principles without overwhelming readers with complex math, empowering them to comprehend the underlying mechanisms of various algorithms and models. This foundational knowledge will enable readers to make informed choices when selecting the right tool for specific problems. In Part II, I focus on the most popular Machine Learning algorithms, including regression methods, decision trees, neural networks, ensemble modeling, principal component analysis, and cluster analysis.