For the last 350 years, since the reign of Elizabeth I, Nicholas Culpeper’s encyclopedic compendium of the uses and properties of medicinal herbs has been unrivaled in completeness or charm. From Adder’s Tongue to Yellow Loosestrife, each of the 316 herbs is described in detail, along with its “government and virtues,” remedies and cautions—much of which has held up remarkably well through many advancements in scientific understanding.