For the first time in Russian, modern data on the use of preservatives in the production of cosmetics and hygiene products were collected and systematized. The analytical review considers such topics as: microorganisms in cosmetic products, sources of pollution, the choice of antimicrobial preservatives, control methods, cosmetics without preservatives, modern packaging as a way of preserving the product, allergies to preservatives, preservative mixtures, as well as legislative aspects in various countries, reference tables with technical data of seventy individual preservatives, microbiological standards.