In the twenties of the 16th century, Belarusian Francis Skorin moved from Prague to Vilnius "in medicine and in the sciences of the rescued doctor." But it was not medicines and medical supplies that Skorin brought with him, but books and printing equipment. And soon a significant event took place - the first Russian-Slavic books were published - "Apostle" and "Small Road Book." In the last quarter of the 16th century, Vilnius already had a whole network of printing houses of various directions: Orthodox, Protestant, Catholic.