Contains methodological materials for preparation for classes on chemical-toxicological and forensic-chemical analysis. Information on the analytical diagnosis of acute poisoning and drug addiction, biotransformation of foreign compounds in the body, analytical toxicology, which includes a description of sample preparation methods, chromatographic, chemical and immunochemical research methods, atomic spectrometry methods, is presented. For students of higher education institutions in medical specialties, it will also be useful for students studying in pharmaceutical specialties, specialists in chemical-toxicological and forensic-chemical laboratories.