This publication is the world famous guide by E. Braunwald "Heart Diseases." It discusses in detail the changes in the epidemiological situation in the world, discusses the reasons for these changes, the importance of individual factors, and gives a forecast for the future. Of considerable interest will be the chapters on the role of molecular biology and genetic factors in the development of CVD. Methods for assessing the patient's health and evaluating the results of various examination methods are discussed. Several chapters cover the pathophysiological mechanisms of the development of various CVDs, the diagnosis and treatment of acute and chronic forms of diseases. Preventive cardiology is presented in chapters on atherothrombotic complications and their risk factors. Non-drug methods for the prevention and rehabilitation of patients with CVD, as well as drug methods for the correction of risk factors and clinically pronounced forms of CVD are described in detail.