The manual outlines the fundamental concepts of the subject of physical chemistry, the main provisions of the theory of the atomic-molecular structure of matter, quantum mechanics, chemical thermodynamics and kinetics of processes. The mathematical apparatus of the manual is adapted to the study of first-year students who do not have a sufficient knowledge of higher mathematics. Corresponds to the university bachelor's program in the direction of "Chemistry." It can be useful for chemistry teachers, students of chemical colleges, technical schools and non-chemical universities.