The manual outlines the physical and technological foundations of nanoelectronics, including the principles of functioning and characteristics of nanoelectronic devices based on quantum-size structures: resonance-tunneling, single-electron and spintronic devices. Features of quantum computers, electronic devices on superconductors, as well as nanobioelectronics devices are considered. Each chapter is equipped with control questions and tasks for self-preparation. For technical students, graduate students, teachers and practitioners in the field of electronics.