Placed information on infectious, invasive and non-contagious diseases of bees, methods of their diagnosis, treatment and prevention. Attention is paid to the description of the biology of pests. their habitats, damage, control and prevention measures. The second edition of the handbook provides methods for the use of new therapeutic agents for varroatosis and other diseases of bees. The principles of general prevention, veterinary and sanitary requirements for apiaries and their protection from the introduction of diseases, zoohygenic standards for keeping and feeding bees, rules for monitoring the quality of bee products, a system for organizing, planning and conducting measures to combat bee diseases in apiaries are outlined. The directory is designed for veterinary specialists, beekeeping workers, tenants, farmers and amateur beekeepers.