Applied sciences, both physical and social, such as atmospheric, biological, climate, demographic, economic, ecological, environmental, oceanic and political, routinely gather large volumes of spatial and spatio-temporal data in order to make wide ranging inference and prediction. Ideally such inferential tasks should be approached through modelling, which aids in estimation of uncertainties in all conclusions drawn from such data. Unified Bayesian modelling, implemented through user friendly software packages, provides a crucial key to unlocking the full power of these methods for solving challenging practical problems.