The training manual covers general issues of ecotoxicology, including population and biocenotic aspects, ecotoxicological characterization of priority pollutants, toxicometry methods, including cumulative and combined effects. Designed for students studying in areas of 06.03.01; 06.04.01 - "Biology" and 05.03.06; 05.04.06 - "Ecology and nature management," graduate students and specialists interested in ecotoxicology.