The manual presents in a structured, concise and accessible form material on the metabolism of proteins, carbohydrates, lipids, hormones, water, minerals, porphyrins, hemoglobin and bile pigments - the main sections of clinical biochemistry. The role of various enzymes in metabolic processes is considered. Special chapters are devoted to acid-base conditions and disorders of hemostasis. Each chapter contains brief theoretical information on the main types of metabolism in the norm and pathology and practical recommendations on the use of biochemical methods to assess metabolic disorders in various pathological conditions. The publication contains 20 figures and 17 tables.