The monograph at a high professional level highlights the social, clinical and psychopathological aspects of the formation and prevention of depressive disorders in patients with alcoholism. Modern and scientifically verified practical recommendations for improving therapeutic measures, taking into account social and clinical risk factors in the formation of depressive disorders in patients with alcohol dependence syndrome, have been demonstrated. Recommended to students of postgraduate professional education studying in psychiatric, narcological, psychotherapeutic specialties, as well as senior students of medical universities, residents, clinical psychologists.