This book discusses in-depth role of optimization to optimize the controller parameters with reference to bio-inspired algorithms. Comparative studies to evaluate the performance of different optimization techniques in terms of the settling time, overshoot and undershoot responses of the frequency deviations, tie-line power flow deviations, and the area control error are included, supported by examples. The book also includes different scenarios of the load frequency controller for single area as well as multi-area thermal power generating unit considering different algorithms.