The scientific picture of the world is considered as one of the most important values ​ ​ of the culture of technogenic civilization. The structure of the scientific picture of the world, its functions in the processes of generating new knowledge and its inclusion in culture are analyzed. The main historical stages of the development of the scientific picture of the world are traced. Its role is revealed in the modern processes of cross-cultural interaction, the search for new worldview guidelines and strategies for civilizational development as a condition for overcoming modern global crises. Addressed to specialists in the field of philosophy, cultural studies, methodology and history of science.