The book "Basic Principles of Prevention and Treatment of Thrombosis" ed., O.N. Tkacheva, considers the hemostasis system in terms of schemes and tables. The physiology of homeostasis, its pathological processes, clinical manifestations are presented. Pharmacotherapy of thrombosis is highlighted. Antithrombotic drugs and their pharmacological properties are presented. Also considered are the treatment of thrombosis in patients with combined pathology, in the elderly, pregnant women. Thrombosis prevention issues were considered. For medical students, surgeons, SMP doctors, cardiologists, neurologists, therapists, oncologists.