Coloring for children is one of the most affordable ways to organize productive developmental work with preschool children. The proposed coloring has a thematic orientation, with its help an adult (teacher or parent) will be able to organize work with children 4-6 years old to form the prerequisites for interhemispheric interaction. Coloring includes tasks built on the basis of the integration of visual (visual) and fine-motor interaction. Performing tasks with the right, then left hand and two hands at the same time, the child turns on both hemispheres of the brain, which allows expanding the boundaries of interhemispheric interaction, improving the synchronization of the right and left hemispheres.