The purpose of the proposed manual is to present in a concise form the main sections of toxicological chemistry: poisons and poisoning, introduction to narcology, drug safety, pesticide determination, etc. The structure of each section maximally facilitates the practical development of the science of methods for determining toxic substances and products of their metabolism in the analysis of biomaterials and other objects. At the end of the book are answers to test questions to control the assimilation of educational material.