This entirely new essay collection brings together pioneers in design within architecture, construction, engineering, manufacturing, materials technology and computation to explore the progressive integration of digital design with manufacturing processes, and its impact on design and making in the 21st century. Discussion on key themes include: how digital fabrication technologies are enabling new creative and construction opportunities from component to building scales, the difficult gap that exists between digital modelling and its realization, material performance and manipulation, off-site and on-site construction, interdisciplinary education, economic and sustainable contexts.