This book provides a comprehensive coverage of Machine Learning (ML) methods that have proven useful in process industry for dynamic process modeling. Step-by-step instructions, supported with industry-relevant case studies, show (using Python) how to develop solutions for process modeling, process monitoring, etc., using classical and modern methods. This book is designed to help readers gain a working-level knowledge of machine learning-based dynamic process modeling techniques that have proven useful in process industry. Readers can leverage the concepts learned to build advanced solutions for process monitoring, soft sensing, inferential modeling, predictive maintenance, and process control for dynamic systems. The application-focused approach of the book is reader friendly and easily digestible to the practicing and aspiring process engineers, and data scientists. No prior experience with Machine Learning or Python is needed. Undergraduate-level knowledge of basic linear algebra and calculus is assumed.