Just as European Jews were being emancipated and ghettos in their original form?compulsory, enclosed spaces designed to segregate?were being dismantled, use of the word ghetto surged in Europe and spread around the globe. Tracing the curious path of this loaded word from its first use in sixteenth-century Venice to the present turns out to be more than an adventure in linguistics.Few words are as ideologically charged as ghetto. Its early uses centered on two cities: Venice, where it referred to the segregation of the Jews in 1516, and Rome, where the ghetto survived until the fall of the Papal States in 1870, long after it had ceased to exist elsewhere.