The book focuses on the role of the Leonardo da Vinci projects and inventions, specifically the interdisciplinarity of his studies that represents perhaps the first example of the paradigm of complex systems engineering. The projects are characterized within a modern conception of his thinking, looking at the main motivations behind his machines. The book also proposes a set of experimental realizations of the models made mainly in wood, using the actual concept of automatic control and microcontroller technology emphasizing that the Leonardo machines can be seen in agreement with modern current technology.