The manual presents modern methods used in immunology and in various fields of biology and medicine. Along with classical methods for isolating cells of the immune system, studying their functional activity, immunoassay methods, studies of gene expression by PCR, microarrays, directed mutagenesis, hybridoma biotechnology, etc. are covered in detail. A comprehensive approach to assessing the cytokine system, one of the important regulatory systems of the body, is presented.