In this manual, much attention is paid to drugs used in the treatment of acne, approaches to the treatment of various forms of the disease. The manual contains a modern review of the literature on the etiology and pathogenesis of acne, details clinical forms of the disease, a diagnostic algorithm for examining patients, and pharmacotherapy data. The methodological manual is intended for dermatovenerologists, cosmetologists, and can also be useful to doctors of other specialties. The manual can be used to train senior students of medical universities and cadets of departments for advanced medical studies.