The monograph is devoted to the problem of high-temperature synthesis of intermetallic compounds. It describes the laws and mechanism of formation of intermetallic compounds in mixtures of metal powders in isothermal and non-isothermal conditions. Particular attention is paid to the self-propagating high-temperature synthesis of intermetallics in combustion mode. Thermodynamic and kinetic aspects of interaction of components in synthesis of intermetallic compounds are considered. Data on physicochemical properties of synthesis products and their application are presented.