This updated edition of an Artech House classic introduces readers to the importance of engineering in medicine. Bioelectrical phenomena, principles of mass and momentum transport to the analysis of physiological systems, the importance of mechanical analysis in biological tissues organs and biomaterial selection are discussed in detail. Readers learn about the concepts of using living cells in various therapeutics and diagnostics, compartmental modeling, and biomedical instrumentation. The book explores fluid mechanics, strength of materials, statics and dynamics, basic thermodynamics, electrical circuits, and material science. A significant number of numerical problems have been generated using data from recent literature and are given as examples as well as exercise problems. These problems provide an opportunity for comprehensive understanding of the basic concepts, cutting edge technologies and emerging challenges.