The textbook presents data on the etiology and pathogenesis of gout, describes clinical manifestations, methods of modern diagnostics, algorithms for treating gout and its complications. Self-monitoring questions, tests and situational clinical tasks are offered to control knowledge. The manual is drawn up in accordance with the current GEF in the specialty 31.05.01 "General Medicine." Designed for independent work of students of IV-VI courses of medical universities, residents, graduate students, students of FDPO, general practitioners, general practitioners, rheumatologists.