The book is devoted to the protection of confidential information and, first of all, personal data, in institutions (organizations - according to the Federal Law of November 21, 2011 No. 323-FZ) of health and social protection. It analyzes the current state of medical information systems in relation to the prospects for introducing information protection tools. The requirements for the protection of information constituting medical confidentiality and personal data of patients are discussed. The main methods and methods of information protection are considered in relation to standard business processes of an average medical and preventive institution. Issues of reducing the category of stored and processed personal data are discussed. The prospects for the development of medical information systems and information security systems are analyzed.