The book deals with the problem of complex depression. It contains an analysis of the results of modern research, taking into account the paradigm shift and epistemological changes in the spirit of the times. The authors summarize current views on the relationships between depression and personality, treating depression as a multifactorial and multilevel phenomenon, and personality disorders as a multidimensional concept. The analysis is carried out through the prism of functional domains that are affected in depression combined with personality dysfunction. Clinical examples provide specific models of the relationship between depression and personality disorders.