The teaching manual contains information on basic issues of pedagogy and teaching methods in higher education, tasks for self-control and independent work of graduate students. The tutorial presents questions for discussion at seminars, test tasks for milestone control, a glossary and a list of recommended literature. The manual is intended for students under the program of training scientific and pedagogical personnel in graduate school in the areas of training "Biological Sciences," "Clinical Medicine," "Culturology," "Medical and Preventive Business," "Pharmacy," "Fundamental Medicine," "Chemical Sciences."