Python Programming is designed to be a textbook for undergraduate and postgraduate students to provide programming knowledge and enhance problem-solving skills. The book begins with the basics of Python programming followed by the basics of algorithms and further focuses on topics like introduction to programming language, looping, functions, and data structures like lists, tuples, sets, dictionary, and strings. It covers functional programming concepts such as higher-order functions. It also covers Object Oriented Programming concepts such as inheritance and polymorphism. The book also deals with modules and packages, errors and exceptions, Python testing, profiling, debugging, and file handling. The book then focuses on GUI programming. An introduction to data analytics, databases, network programming, and security is provided in this book. The book is also helpful for diploma courses, school curricula, competitive examinations like GATE, coding interviews, and coding competitions. This book can also be used for imparting training and certificate courses to professionals. This book is also ideal for self-study who wishes to make a career in the IT field. Whether a beginner or an experienced coder, this book will help readers navigate through Python and enable them to maximize its power, versatility, and general-purpose nature as a programming language.