The textbook sets out modern ideas about the structure and functions of the human body in accordance with the curriculum "Physiology with the basics of anatomy." The morphofunctional features of living systems and basic physiological processes that appear at the level of cells, tissues, organs and the body as a whole are highlighted. The main genomic and epigenomic mechanisms of regulation of intracellular processes, as well as molecular mechanisms of adaptation of cells to the action of environmental factors are presented. The structure and precision neurohumoral mechanisms of the functioning of internal organ systems are described. Reproductive function is considered, the main stages of individual human development are shown. Described are the main systems that mediate immunity, oxygen and circulatory modes, metabolism and energy, as well as the water-electrolyte balance of the body. Information on the role of histohematic barriers in maintaining homeostasis of the human internal environment is presented. The principles of the organization and functioning of the central nervous system are covered, the foundations of perception and psychophysiological relations, the architectonics of the behavioral act, human biorhythms, as well as neurophysiological mechanisms of pain are considered. Meets the requirements of the latest generation of federal state educational standards for higher education. For students of specialty pharmaceutical universities and faculties studying in the specialty 33.05.01 "Pharmacy." It can be used as additional educational literature by students of medical universities.