This book explores cross-cultural medical encounters involving non-Western healers in a variety of imperial contexts from the Arctic, Asia, Africa, Americas and the Caribbean. It highlights contests over healing, knowledge and medicines through the frameworks of hybridisation and pluralism. The intertwined histories of medicine, empire and early globalisation influenced the ways in which millions of people encountered and experienced suffering, healing and death. In an increasingly global search for therapeutics and localised definition of acceptable healing, networks and mobilities played key roles.