The manual is devoted to the consideration of basic constructions of the Python language, in particular, first there are examples of the simplest programs in the imperative programming style and examples of solving simple problems of a linear, branching and cyclic structure, problems with sequences and files. The following is an implementation in the form of Python programs of algorithms for computational mathematics methods. Much attention is paid to the practice of using the numpy, matplotlib, pandas and turtle libraries to analyze data and their graphical interpretation.