This book provides and addresses the current challenges, approaches, and applications relating to autonomous vehicles, using Internet of Things (IoT), machine learning, deep learning, and Artificial Intelligence (AI) techniques. Several self-driving or autonomous (“driverless”) cars, trucks, and drones incorporate a variety of IoT devices and sensing technologies such as sensors, gyroscopes, cloud computing, and fog layer, allowing the vehicles to sense, process, and maintain massive amounts of data on traffic, routes, suitable times to travel, potholes, sharp turns, and robots for pipe inspection in the construction and mining industries.